Инд. авторы:	Dubovskiy I.M., Grizanova E.V., Ershova N.S., Rantala M.J., Glupov V.V.
Заглавие:	The effects of dietary nickel on the detoxification enzymes, innate immunity and resistance to the fungus Beauveria bassiana in the larvae of the greater wax moth Galleria mellonella
Библ. ссылка:	Dubovskiy I.M., Grizanova E.V., Ershova N.S., Rantala M.J., Glupov V.V. The effects of dietary nickel on the detoxification enzymes, innate immunity and resistance to the fungus Beauveria bassiana in the larvae of the greater wax moth Galleria mellonella // Chemosphere. - 2011. - Vol.85. - Iss. 1. - P.92-96. - ISSN 0045-6535. - EISSN 1879-1298 .
Внешние системы:	DOI: 10.1016/j.chemosphere.2011.05.039; PubMed: 21676429; SCOPUS: 2-s2.0-84860389665; WoS: 000295307800013;
Реферат:	eng: In this study, we tested the effects of dietary nickel on the activity of glutathione S-transferase (GST), esterases, phenoloxidase, and encapsulation in the haemolymph of larvae of the greater wax moth Galleria mellonella. We also explored the effects of dietary nickel on larval resistance to infection by the fungus Beauveria bassiana. Larvae fed a low dose of nickel (10 mu g g(-1)) had significantly higher GST, phenoloxidase activity and encapsulation responses than controls fed on a nickel-free diet. We also found that larvae fed a sublethal dose of nickel (50 mu g g(-1)) had increased GST, esterase activity and encapsulation rates but decreased phenoloxidase activity. Although, a sublethal dose of dietary nickel enhanced innate immunity, we found that this reduced resistance against the real pathogen. Our results suggest that enhanced immunity and detoxification enzyme activity of insects may not be beneficial to resistance to fungal infection. It appears that there is a trade off between different resistance mechanisms in insects under different metal treatments. (C) 2011 Elsevier Ltd. All rights reserved.
Ключевые слова:	XENOBIOTICS; LEPIDOPTERA; ENCAPSULATION; GEOMETRID MOTH; DETOXIFYING ENZYMES; BACTERIAL-INFECTION; EPIRRITA-AUTUMNATA; LITURA FABRICIUS LARVAE; HEAVY-METAL POLLUTION; Detoxification system; Heavy metals; PO; Pathogenesis; Innate immunity; GRADIENT;
Издано:	2011
Физ. характеристика:	с.92-96