Инд. авторы:	Rar V., Livanova N., Tkachev S., Kaverina G., Tikunov A., Sabitova Y., Igolkina Y., Panov V., Livanov S., Fomenko N., Babkin I., Tikunova N.
Заглавие:	Detection and genetic characterization of a wide range of infectious agents in Ixodes pavlovskyi ticks in Western Siberia, Russia
Библ. ссылка:	Rar V., Livanova N., Tkachev S., Kaverina G., Tikunov A., Sabitova Y., Igolkina Y., Panov V., Livanov S., Fomenko N., Babkin I., Tikunova N. Detection and genetic characterization of a wide range of infectious agents in Ixodes pavlovskyi ticks in Western Siberia, Russia // Parasites & Vectors. - 2017. - Vol.10. - Art.258. - ISSN 1756-3305.
Внешние системы:	DOI: 10.1186/s13071-017-2186-5; PubMed: 28545549; SCOPUS: 2-s2.0-85019624234; WoS: 000402334800003;
Реферат:	eng: Background: The Ixodes pavlovskyi tick species, a member of the I. persulcatus/I. ricinus group, was discovered in the middle of the 20th century in the Russian Far East. Limited data have been reported on the detection of infectious agents in this tick species. The aim of this study was to investigate the prevalence and genetic variability of a wide range of infectious agents in I. pavlovskyi ticks collected in their traditional and recently invaded habitats, the Altai Mountains and Novosibirsk Province, respectively, which are both located within the Western Siberian part of the I. pavlovskyi distribution area. Results: This study reports the novel discovery of Borrelia bavariensis, Rickettsia helvetica, R. heilongjiangensis, R. raoultii, 'Candidatus Rickettsia tarasevichiae', Anaplasma phagocytophilum, Ehrlichia muris, 'Candidatus Neoehrlichia mikurensis' and Babesia microti in I. pavlovskyi ticks. In addition, we confirmed the previous identification of B. afzelii, B. garinii and B. miyamotoi, as well as tick-borne encephalitis and Kemerovo viruses in this tick species. The prevalence and some genetic characteristics of all of the tested agents were compared with those found in I. persulcatus ticks that were collected at the same time in the same locations, where these tick species occur in sympatry. It was shown that the prevalence and genotypes of many of the identified pathogens did not significantly differ between I. pavlovskyi and I. persulcatus ticks. However, I. pavlovskyi ticks were significantly more often infected by B. garinii and less often by B. bavariensis, B. afzelii, 'Ca. R. tarasevichiae', and E. muris than I. persulcatus ticks in both studied regions. Moreover, new genetic variants of B. burgdorferi (sensu lato) and Rickettsia spp. as well as tick-borne encephalitis and Kemerovo viruses were found in both I. pavlovskyi and I. persulcatus ticks. Conclusion: Almost all pathogens that were previously detected in I. persulcatus ticks were identified in I. pavlovskyi ticks; however, the distribution of species belonging to the B. burgdorferi (sensu lato) complex, the genus Rickettsia, and the family Anaplasmataceae was different between the two tick species. Several new genetic variants of viral and bacterial agents were identified in I. pavlovskyi and I. persulcatus ticks. © 2017 The Author(s).
Ключевые слова:	Virus Diseases; Tick-Borne Diseases; Siberia; Ixodes; Humans; Bacterial Infections; Bacteria; Arthropod Vectors; Animals; virus infection; virus; virology; transmission; tick borne disease; Russian Federation; physiology; microbiology; Ixodes; isolation and purification; human; genetics; classification; bacterium; bacterial infection; arthropod vector; animal; Tick borne encephalitis virus; sympatry; Russian Federation; Rickettsia helvetica; prevalence; Orbivirus; nonhuman; Ixodes persulcatus; habitat; genus; genetic variability; genetic trait; family; Ehrlichia muris; Borrelia burgdorferi; Babesia microti; Anaplasma phagocytophilum; Western Siberia; Tick-borne encephalitis virus; Rickettsia spp; Kemerovo virus; Viruses; Ixodes pavlovskyi; Borrelia miyamotoi; Borrelia burgdorferi (sensu lato); Babesia microti; Anaplasmataceae; Ixodes persulcatus;
Издано:	2017
Физ. характеристика:	258