Инд. авторы:	Dubovskiy I.M., Whitten M.A., Kryukov V.Y., Yaroslavtseva O.N., Grizanova E.V., Greig C., Mukherjee K., Vilcinskas A., Mitkovets P.V., Glupov V.V., Butt T.M.
Заглавие:	More than a colour change: insect melanism, disease resistance and fecundity
Библ. ссылка:	Dubovskiy I.M., Whitten M.A., Kryukov V.Y., Yaroslavtseva O.N., Grizanova E.V., Greig C., Mukherjee K., Vilcinskas A., Mitkovets P.V., Glupov V.V., Butt T.M. More than a colour change: insect melanism, disease resistance and fecundity // Proceedings of the Royal Society B-Biological Sciences. - 2013. - Vol.280. - Iss. 1763. - Art.UNSP 20130584. - ISSN 0962-8452. - EISSN 1471-2954.
Внешние системы:	DOI: 10.1098/rspb.2013.0584; PubMed: 23698007; SCOPUS: 2-s2.0-84892389775; WoS: 000320232000003;
Реферат:	eng: A 'dark morph' melanic strain of the greater wax moth, Galleria mellonella, was studied for its atypical, heightened resistance to infection with the entomo-pathogenic fungus, Beauveria bassiana. We show that these insects exhibit multiple intraspecific immunity and physiological traits that distinguish them from a non-melanic, fungus-susceptible morph. The melanic and non-melanic morphs were geographical variants that had evolved different, independent defence strategies. Melanic morphs exhibit a thickened cuticle, higher basal expression of immunity- and stress-management-related genes, higher numbers of circulating haemocytes, upregulated cuticle phenoloxidase (PO) activity concomitant with conidial invasion, andanenhanced capacitytoencap-sulate fungal particles. These insects prioritize specific augmentations to those frontline defences that are most likely to encounter invading pathogens or to sustain damage. Other immune responses that target late-stage infection, such as haemolymph lysozyme and PO activities, do not contribute to fungal tolerance. The net effect is increased larval survival times, retarded cuticular fungal penetration and a lower propensity to develop haemolymph infections when challenged naturally (topically) and by injection. In the absence of fungal infection, however, the heavy defence investments made by melanic insects result in a lower biomass, decreased longevity and lower fecundity in comparison with their non-melanic counterparts. Although melanism is clearly correlated with increased fungal resistance, the costly mechanisms enabling this protective trait constitute more than just a colour change. © 2013 The Author(s) Published by the Royal Society. All rights reserved.
Ключевые слова:	Melanosis; Larva; Insects; Insect Proteins; Host-Pathogen Interactions; Gene Expression Regulation; Fertility; Disease Resistance; Beauveria; Animals; physiology; moth; microbiology; metabolism; melanosis; larva; insect; immunology; host pathogen interaction; genetics; gene expression regulation; fertility; disease resistance; Beauveria; animal; insect protein; physiological response; pathogen; moth; melanism; longevity; larval development; immunity; fungus; fecundity; enzyme activity; entomopathogenic organism; disease resistance; cuticle; color; Moths; Resistance; Melanism; Insect-pathogenic fungus; Insect; Immunity; Stress;
Издано:	2013