| Инд. авторы: | Kryukova N.A., Chertkova E.A., Semenova A.D., Glazachev Y.I., Slepneva I.A., Glupov V.V. |
| Заглавие: | VENOM FROM THE ECTOPARASITIC WASP Habrobracon hebetor ACTIVATES CALCIUM-DEPENDENT DEGRADATION OF Galleria mellonella LARVAL HEMOCYTES |
| Библ. ссылка: | Kryukova N.A., Chertkova E.A., Semenova A.D., Glazachev Y.I., Slepneva I.A., Glupov V.V. VENOM FROM THE ECTOPARASITIC WASP Habrobracon hebetor ACTIVATES CALCIUM-DEPENDENT DEGRADATION OF Galleria mellonella LARVAL HEMOCYTES // Archives of Insect Biochemistry and Physiology. - 2015. - Vol.90. - Iss. 3. - P.117-130. - ISSN 0739-4462. - EISSN 1520-6327. |
| Внешние системы: | DOI: 10.1002/arch.21247; PubMed: 26089096; SCOPUS: 2-s2.0-84945485904; WoS: 000363470000001; |
| Реферат: | eng: Ectoparasitoids inject venom into hemolymph during oviposition. We determined the influence of envenomation by the parasitoid, Habrobracon hebetor, on the hemocytes of its larval host, Galleria mellonella. An increase in both intracellular Ca2+ content and phospholipase C activity of the host hemocytes was recorded during 2 days following envenomation by the parasitoid. The decreased hemocyte viability was detected 1, 2, and 24 h after the envenomation. Injecting of the crude venom (final protein concentration 3 μg/ml) into the G. mellonella larvae led to the reduced hemocyte adhesion. The larval envenomation caused a decrease in transmembrane potential of the hemocytes. These findings document the suppression of hemocytic immune effectors in the parasitized host larvae. © 2015 Wiley Periodicals, Inc.
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| Ключевые слова: | Wasp Venoms; Type C Phospholipases; Moths; Membrane Potentials; Larva; Host-Parasite Interactions; Hemolymph; Hemocytes; Cell Survival; Cell Adhesion; Calcium; Animals; wasp; physiology; parasitology; moth; metabolism; Wasps; larva; host parasite interaction; hemolymph; drug effects; cytology; cell survival; cell adhesion; blood cell; animal; wasp venom; phospholipase C; calcium; Venom; Transmembrane potential; Hemocytes; Habrobracon hebetor; Free cytosolic calcium; membrane potential; |
| Издано: | 2015 |
| Физ. характеристика: | с.117-130 |