Инд. авторы:	Колпакова А.Ф.
Заглавие:	О возможностях применения прямого ингибитора ренина алискирена для лечения социально значимых заболеваний
Библ. ссылка:	Колпакова А.Ф. О возможностях применения прямого ингибитора ренина алискирена для лечения социально значимых заболеваний // Сибирский медицинский журнал (Томск). - 2014. - Т.29. - № 2. - С.14-21. - ISSN 2073-8552.
Внешние системы:	РИНЦ: 23598686;
Реферат:	rus: В обзоре проанализированы результаты рандомизированных исследований эффективности и безопасности прямого ингибитора ренина алискирена при лечении больных артериальной гипертонией в сочетании с ожирением, сахарным диабетом, менопаузой и поражением почек; хронической болезнью почек, метаболическим синдромом. Установлено, что алискирен обладает не только гипотензивным, но кардио- и ренопротективным действием, что может расширить показания к его применению. eng: This review analyzes the results of randomized studies of the efficacy and safety of direct renin inhibitor aliskiren in the treatment of patients with arterial hypertension associated with obesity, diabetes, menopause, kidney failure, chronic kidney disease, and metabolic syndrome. The authors conclude that, along with the hypotensive action, aliskiren exerts cardioprotective and renoprotective effects that can expand the indications for the use of this drug.
Ключевые слова:	эффективность и безопасность лечения; прямой ингибитор ренина; organoprotective effect; efficacy and safety of treatment; Direct renin inhibitor; органопротективный эффект;
Издано:	2014
Физ. характеристика:	с.14-21
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