| Инд. авторы: | Zakharov B.A., Seryotkin Y.V., Tumanov N.A., Paliwoda D., Hanfland M., Kurnosov A.V., Boldyreva E.V. |
| Заглавие: | The role of fluids in high-pressure polymorphism of drugs: Different behaviour of β-chlorpropamide in different inert gas and liquid media |
| Библ. ссылка: | Zakharov B.A., Seryotkin Y.V., Tumanov N.A., Paliwoda D., Hanfland M., Kurnosov A.V., Boldyreva E.V. The role of fluids in high-pressure polymorphism of drugs: Different behaviour of β-chlorpropamide in different inert gas and liquid media // RSC Advances. - 2016. - Vol.6. - Iss. 95. - P.92629-92637. - ISSN 2046-2069. |
| Внешние системы: | DOI: 10.1039/c6ra17750f; SCOPUS: 2-s2.0-84989318889; WoS: 000385389800057; |
| Реферат: | eng: The hydrostatic compression of β-chlorpropamide gives different high-pressure phases, depending on the choice of pressure-transmitting fluid (paraffin, neon and helium). This is particularly surprising as none of these fluids interact obviously with the solid at ambient pressure. This phenomenon is not related to dissolution and recrystallization, in contrast to what has been previously observed for β-chlorpropamide in a 1:1 pentane-isopentane mixture. © 2016 The Royal Society of Chemistry.
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| Ключевые слова: | Inert gases; Pentane isopentane; Liquid media; Hydrostatic compression; High-pressure phasis; High pressure polymorphism; Ambient pressures; Paraffins; |
| Издано: | 2016 |
| Физ. характеристика: | с.92629-92637 |