| Инд. авторы: | Vechkapova S.O., Zapara T.A., Morozova E.A., Proskura A.L., Schul'ts E.E., Tolstikova T.G., Ratushnyak A.S. |
| Заглавие: | Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections |
| Библ. ссылка: | Vechkapova S.O., Zapara T.A., Morozova E.A., Proskura A.L., Schul'ts E.E., Tolstikova T.G., Ratushnyak A.S. Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections // Bulletin of Experimental Biology and Medicine. - 2016. - Vol.161. - Iss. 6. - P.782-785. - ISSN 0007-4888. - EISSN 1573-8221. |
| Внешние системы: | DOI: 10.1007/s10517-016-3509-9; SCOPUS: 2-s2.0-84992365752; WoS: 000387594400011; |
| Реферат: | eng: Amide of lambertian acid suppresses hyperactivation of inotropic glutamate receptors in hippocampal sections induced by a decrease in the level of magnesium ions (a selective blocker of glutamate NMDA receptors). Treatment of the sections with amide of lambertian acid in standard physiological saline does not prevent development of NMDA-dependent synaptic potentiation. Lambertian acid isolated from needles and turpentine of Siberian pine (Pinus sibirica R. Mayr), and its derivatives may become a source of substances with glutamatergic mechanism of action for treatment of cognitive and neurodegenerative disorders.
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| Ключевые слова: | post-tetanic synaptic potentiation; amide of lambertian acid; hyperactivation of glutamatergic receptors; SCHIZOPHRENIA; hippocampal sections; |
| Издано: | 2016 |
| Физ. характеристика: | с.782-785 |