Инд. авторы: | Obut T.A., Ovsyukova M.V., Egorova S.A., Erdynieva T.A., Dementeva T.Yu., Obut E.T., Gorobchuk A.G. |
Заглавие: | Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures |
Библ. ссылка: | Obut T.A., Ovsyukova M.V., Egorova S.A., Erdynieva T.A., Dementeva T.Yu., Obut E.T., Gorobchuk A.G. Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures // Bulletin of Experimental Biology and Medicine. - 2014. - Vol.157. - Iss. 2. - P.231-233. - ISSN 0007-4888. - EISSN 1573-8221. |
Внешние системы: | DOI: 10.1007/s10517-014-2532-y; РИНЦ: 22775254; WoS: 000339005200014; |
Реферат: | eng: Male rats were exposed to single or repeated (19 days) cold treatment (4°C) and non-cold stress (60-min shaking on a laboratory shuttle device). Retabolil had a hypotensive effect, which was accompanied by the prevention of a stress-induced increase in the concentration of a hypertensive hormone aldosterone. Under conditions of repeated stress, these effects were realized via μ-opioid receptors. Our results suggest that retabolil can be used as a hypotensive and aldosterone-blocking agent, at least during stress exposure in animals (and probably in humans). |
Ключевые слова: | retabolil aldosterone blood pressure stress exposures μ-opioid receptors; |
Издано: | 2014 |
Физ. характеристика: | с.231-233 |
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