Инд. авторы: Obut T.A., Ovsyukova M.V., Egorova S.A., Erdynieva T.A., Dementeva T.Yu., Obut E.T., Gorobchuk A.G.
Заглавие: Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures
Библ. ссылка: Obut T.A., Ovsyukova M.V., Egorova S.A., Erdynieva T.A., Dementeva T.Yu., Obut E.T., Gorobchuk A.G. Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures // Bulletin of Experimental Biology and Medicine. - 2014. - Vol.157. - Iss. 2. - P.231-233. - ISSN 0007-4888. - EISSN 1573-8221.
Внешние системы: DOI: 10.1007/s10517-014-2532-y; РИНЦ: 22775254; WoS: 000339005200014;
Реферат: eng: Male rats were exposed to single or repeated (19 days) cold treatment (4°C) and non-cold stress (60-min shaking on a laboratory shuttle device). Retabolil had a hypotensive effect, which was accompanied by the prevention of a stress-induced increase in the concentration of a hypertensive hormone aldosterone. Under conditions of repeated stress, these effects were realized via μ-opioid receptors. Our results suggest that retabolil can be used as a hypotensive and aldosterone-blocking agent, at least during stress exposure in animals (and probably in humans).
Ключевые слова: retabolil aldosterone blood pressure stress exposures μ-opioid receptors;
Издано: 2014
Физ. характеристика: с.231-233
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